This is your basic spread option five WR set. Your two outside WRs run 9 routes (post) and the 3 inside guys run 6 routes (comebacks). this is very similar to our All Ins (66666) or All Comebacks play, and you can run it right afterwards. It's nearly unstoppable. 

The safeties will see everyone coming back and start screaming "all in". In fact, your QB can scream "all ins" at the line, or "all comebacks" to tell the defense the play. Or just yell, "same play, same play" at the line.

Use mind games as much as you do Xs and Os.

The QB will have plenty of options to choose from. Regardless of the defense being played, this play will overwhelm the secondary. They just won't have enough guys to cover everyone. But they will be able to rush in fast, since you don't have tight ends to help pass protect.

Make sure your QB is good at throwing and make sure he gets it to your most athletic WR, the rest are distractors.

If the safeties stay high, get it to one of the underneath 6 routes. If the safeties clamp down fire it off to one of the outside 9 routes deep.