This play can be used in flag football, backyard football and in organized football. Just add the tightends, runningbacks and extra linemen.
This play is a direct snap to the WR. The WR goes in motion from the weak side to the strong side. The ball is snapped straight to the WR, either silently or when the QB says hike. The other two WR block for the run. One takes on the oncoming LB, the other the CB on that side. If they have two CB, you adjust by having the WR block the CBs and the OL man on the far right attack the LB. The other LBs may be too slow to catch up.
The QB can make this play even trickier by saying something like, "Hey John, you're supposed to be on the other side, pointing to the right." The WR that is supposed to go into motion realizes he is out of place and motions to the other side, receiving the direct snap on a silent snap. This is an awesome play fake. Very few defenses can stop this.
In backyard football, you don't always play that the ball must be snapped. A lot of times the QB just holds the ball out in front of him, then says "hike". If you want to use this in backyard football and don't snap the ball in your style of play, you can easily modify this play. Basically, the QB holds the ball out in front of him, motions the WR to the other side. Right before the WR reaches the QB, he says "hike" and the WR grabs the ball that the QB has been holding out in front of him. And the play continues as above.